Alisa Hlans, seven, was one of six people who died when her kindergarten, in the town of Okhtyrka, one hour’s drive from Ukraine’s north-east border, was hit on Friday.

Alisa was three months away from her eighth birthday, according to Prosecutor General Irina Venediktova.

She died in hospital on Saturday.

Children killed in Kharkiv and Kherson

Elsewhere, a teenage girl was reported to have died after being rushed to a hospital in Kharkiv with severe lung damage. The city, just 25 miles from the Russian border, was hit by rocket fire on Wednesday and has been hit by heavy shelling since Monday.

Save the Children reported last week that a 17-year-old boy was killed in an attack on the village of Semikhatky in the southern Kherson region, and two other children were killed in shelling, one in Chuhuiv and the other in Mariupol.

A six-year-old girl called Sofia Fedko and her brother Ivan, who was only a few weeks old, are said to have died when the family came under fire near the southern city of Kherson. The children’s mother Irina and two grandparents, aged 56, also died on the first day of the conflict.

Meanwhile, a local doctor told Sky News that a boy of ten died of gunshot wounds on his way to Ohmatdyt Children’s Hospital in Kyiv on Friday night.

Dr Andrey Vysotskyi said the boy was “in the ambulance and also the ambulance was under gunfire”.